This is an exciting time. As for now, you don't need any physical stuff to work, except a laptop and a wifi connection.
If you need a complex corporate network environment, cloud make it possible to move everything online. (Infrastructure As A Service, is yet an undervalued progress)
If you need people to do repeatitive tasks, you can create process (human process, or software process) so you can find people fitting your need more easily... everywhere in the world.
If you need to be notified when anything happen, you can use SMS, lightbulb, mails, twitter, facebook with tablet or cellphone or computer or whatever channel of communication you ever want.
Everything exists, the hard part is to decide which notification is important to deserve your attention, and which one should be kept out of your eyes, the technical part of the solution already exist.
You will certainly agree with this point. But like most people, you might not yet use it to your advantage. You might consume killer apps, or using killer website, or killer tablet, but the problem is that you consider it like a tool.
These are not tools, these are part of a personal information system that support your decision and extend your reach. This system should follow you and evolve through your life.
Nobody will have the same system, because nobody have the same life, so you can't expect someone to do it for you.
A business should be considered as an autonomous information system that will integrate with your personal one at the beginning. The goal is to reach the point where you can unplug from this system, without it dying.
An entrepreneur that sells or quits its business that just crash without him is a business failure for the entrepreneur.
With this definition Steve Jobs can be considered an entrepreneur failure if Apple can't stand without him. Whatever the genius in marketing or vision, the great business should thrives without someone holding its hand.
As I've not created any successful business yet, this definition will drive my choices, and is the ultimate metric I need will use to track my progress. Does it stand without me ?